Nikethamide

Nikethamide
Clinical data
Other names	Nicotinic acid diethylamide
AHFS/Drugs.com	International Drug Names
ATC code	R07AB02 (WHO) ;
Pharmacokinetic data
Elimination half-life	0.5 h
Identifiers
	IUPAC name N,N-Diethyl-3-pyridinecarboxamide;
CAS Number	59-26-7 ;
PubChem CID	5497;
DrugBank	DB13655;
ChemSpider	5296 ;
UNII	368IVD6M32;
KEGG	D07408 ;
ChEBI	CHEBI:134814;
ChEMBL	ChEMBL2104607;
CompTox Dashboard (EPA)	DTXSID9046524 ;
ECHA InfoCard	100.000.380
Chemical and physical data
Formula	C10H14N2O
Molar mass	178.235 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N(CC)CC)c1cccnc1;
	InChI InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3 ; Key:NCYVXEGFNDZQCU-UHFFFAOYSA-N ;
	(verify)

Nikethamide is a stimulant which mainly affects the respiratory cycle. Widely known by its former trade name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is no longer commonly considered to be of value for such purposes.

In alternate terminology, it is known as nicotinic acid diethylamide, which meaningfully emphasizes its laboratory origins, and of which its common name is derived as a blend.