Node of Ranvier

Node of Ranvier
Drawing of a peripheral nerve axon (labeled "axis cylinder"), showing a node of Ranvier along with other features
Nodes of Ranvier
Details
SystemNervous system
LocationMyelinated axon of a nerve
Identifiers
Latinincisura myelini
MeSHD011901
THH2.00.06.2.03015
Anatomical terms of microanatomy

In neuroscience and anatomy, nodes of Ranvier (/ˈrɑːnvi/ RAHN-vee-ay),[1][2] also known as myelin-sheath gaps, occur along a myelinated axon where the axolemma is exposed to the extracellular space. Nodes of Ranvier are uninsulated and highly enriched in ion channels, allowing them to participate in the exchange of ions required to regenerate the action potential. Nerve conduction in myelinated axons is referred to as saltatory conduction (from Latin saltus 'leap, jump') due to the manner in which the action potential seems to "jump" from one node to the next along the axon. This results in faster conduction of the action potential.

  1. ^ "node of Ranvier". Lexico UK English Dictionary. Oxford University Press. Archived from the original on October 16, 2021.
  2. ^ "node of Ranvier". Merriam-Webster.com Dictionary.

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