Ocinaplon

Ocinaplon
Clinical data
ATC code	none;
Identifiers
	IUPAC name pyridin-2-yl-(7-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl)methanone;
CAS Number	96604-21-6 ;
PubChem CID	216456;
IUPHAR/BPS	4277;
ChemSpider	187602 ;
UNII	2H6KVC5E76;
KEGG	D02617 ;
CompTox Dashboard (EPA)	DTXSID00242362 ;
Chemical and physical data
Formula	C17H11N5O
Molar mass	301.309 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1cnn2c(ccnc12)c3ccncc3)c4ncccc4;
	InChI InChI=1S/C17H11N5O/c23-16(14-3-1-2-7-19-14)13-11-21-22-15(6-10-20-17(13)22)12-4-8-18-9-5-12/h1-11H ; Key:OQJFBUOFGHPMSR-UHFFFAOYSA-N ;
	(verify)

Ocinaplon is an anxiolytic drug in the pyrazolopyrimidine family of drugs. Other pyrazolopyrimidine drugs include zaleplon and indiplon.

Ocinaplon has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and relatively little sedative or amnestic effect.^[1]

^ Lippa A, Czobor P, Stark J, Beer B, Kostakis E, Gravielle M, et al. (May 2005). "Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator". Proceedings of the National Academy of Sciences of the United States of America. 102 (20): 7380–5. Bibcode:2005PNAS..102.7380L. doi:10.1073/pnas.0502579102. PMC 1129138. PMID 15870187.

[1] Lippa A, Czobor P, Stark J, Beer B, Kostakis E, Gravielle M, et al. (May 2005). "Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator". Proceedings of the National Academy of Sciences of the United States of America. 102 (20): 7380–5. Bibcode:2005PNAS..102.7380L. doi:10.1073/pnas.0502579102. PMC 1129138. PMID 15870187.

[1]

Clinical data

ATC code	none
Identifiers
IUPAC name pyridin-2-yl-(7-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-3-yl)methanone
CAS Number	96604-21-6^Y
PubChem CID	216456
IUPHAR/BPS	4277
ChemSpider	187602^Y
UNII	2H6KVC5E76
KEGG	D02617^Y
CompTox Dashboard (EPA)	DTXSID00242362
Chemical and physical data
Formula	C₁₇H₁₁N₅O
Molar mass	301.309 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(c1cnn2c(ccnc12)c3ccncc3)c4ncccc4
InChI InChI=1S/C17H11N5O/c23-16(14-3-1-2-7-19-14)13-11-21-22-15(6-10-20-17(13)22)12-4-8-18-9-5-12/h1-11H^Y Key:OQJFBUOFGHPMSR-UHFFFAOYSA-N^Y
(verify)