Oripavine

Oripavine

Names
IUPAC name 6,7,8,14-Tetradehydro-4,5α-epoxy-6-methoxy-17-methylmorphinan-3-ol
Other names 3-O-desmethylthebaine
Identifiers
CAS Number	467-04-9 N
3D model (JSmol)	Interactive image
ChEBI	CHEBI:7782 Y
ChEMBL	ChEMBL437602 Y
ChemSpider	4575366 Y
ECHA InfoCard	100.006.715
EC Number	207-385-6
KEGG	C06175 N
MeSH	Oripavine
PubChem CID	5462306
UNII	575AOU51CR N
CompTox Dashboard (EPA)	DTXSID10196908
InChI InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3-6,12,17,20H,7-9H2,1-2H3/t12-,17+,18+/m1/s1 Y Key: ZKLXUUYLEHCAMF-UUWFMWQGSA-N Y InChI=1S/C18H19NO3/c1-19-8-7-18-11-4-6-14(21-2)17(18)22-16-13(20)5-3-10(15(16)18)9-12(11)19/h3-6,12,17,20H,7-9H2,1-2H3/t12-,17+,18+/m1/s1 Key: ZKLXUUYLEHCAMF-UUWFMWQGBL Key: ZKLXUUYLEHCAMF-UUWFMWQGSA-N
SMILES OC1=C(O[C@H]2C(OC)=CC=C3[C@@]42CCN5C)C4=C(C[C@H]35)C=C1
Properties
Chemical formula	C18H19NO3
Molar mass	297.348 g/mol
Pharmacology
ATC code	N02A (WHO)
Routes of administration	SC
Legal status	BR: Class A1 (Narcotic drugs) US: Schedule II
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Oripavine is an opioid and the major metabolite of thebaine. It is the parent compound from which a series of semi-synthetic opioids are derived, which includes the compounds etorphine and buprenorphine. Although its analgesic potency is comparable to morphine, it is not used clinically due to its severe toxicity and low therapeutic index. Due to its use in manufacture of strong opioids, oripavine is a controlled substance in some jurisdictions.