Paralytic | |||||||
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Identifiers | |||||||
Symbol | para | ||||||
Alt. symbols | bss, sbl, olfD, DmNav, DmNav1, DmNav | ||||||
NCBI gene | 32619 | ||||||
UniProt | P35500 | ||||||
Other data | |||||||
Locus | Chr. X 16,455,230 - 16,533,368 | ||||||
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Paralytic is a gene in the fruit fly, Drosophila melanogaster, which encodes a voltage gated sodium channel within D. melanogaster neurons.[1] This gene is essential for locomotive activity in the fly.[1] There are 9 different para alleles, composed of a minimum of 26 exons within over 78kb[2] of genomic DNA.[3] The para gene undergoes alternative splicing to produce subtypes of the channel protein.[3] Flies with mutant forms of paralytic are used in fly models of seizures, since seizures can be easily induced in these flies.[4]
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