Phosphatidic acid

Phosphatidic acids are anionic phospholipids important to cell signaling and direct activation of lipid-gated ion channels. Hydrolysis of phosphatidic acid gives rise to one molecule each of glycerol and phosphoric acid and two molecules of fatty acids. They constitute about 0.25% of phospholipids in the bilayer.^[1]

^ Welti, R; Li, W; Li, M; Sang, Y; Biesiada, H; Zhou, HE; Rajashekar, CB; Williams, TD; Wang, X (30 August 2002). "Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis". The Journal of Biological Chemistry. 277 (35): 31994–2002. doi:10.1074/jbc.M205375200. PMID 12077151.

[1] Welti, R; Li, W; Li, M; Sang, Y; Biesiada, H; Zhou, HE; Rajashekar, CB; Williams, TD; Wang, X (30 August 2002). "Profiling membrane lipids in plant stress responses. Role of phospholipase D alpha in freezing-induced lipid changes in Arabidopsis". The Journal of Biological Chemistry. 277 (35): 31994–2002. doi:10.1074/jbc.M205375200. PMID 12077151.

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