Protein synthesis inhibitor

Simplified schematic of mRNA translation

A protein synthesis inhibitor is a compound that stops or slows the growth or proliferation of cells by disrupting the processes that lead directly to the generation of new proteins.[1]

A ribosome is a biological machine that utilizes protein dynamics on nanoscales to translate RNA into proteins

While a broad interpretation of this definition could be used to describe nearly any compound depending on concentration, in practice, it usually refers to compounds that act at the molecular level on translational machinery (either the ribosome itself or the translation factor),[2] taking advantages of the major differences between prokaryotic and eukaryotic ribosome structures.[citation needed]

  1. ^ Frank Lowy. "Protein Synthesis Inhibitors" (PDF). Columbia University. Retrieved 2021-01-27.
  2. ^ "7.344 Antibiotics, Toxins, and Protein Engineering, Spring 2007". MIT OpenCourseWare.

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