RHAG

RHAG
Identifiers
Aliases	RHAG, CD241, RH2, RH50A, Rh50, Rh50GP, SLC42A1, OHS, OHST, Rh-associated glycoprotein, Rh associated glycoprotein, RHNR
External IDs	OMIM: 180297; MGI: 1202713; HomoloGene: 68045; GeneCards: RHAG; OMA:RHAG - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	49,636,839 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	41,151,645 bp
RNA expression pattern
	Top expressed in
	trabecular bone; ; bone marrow; ; bone marrow cells; ; testicle; ; blood; ; right auricle; ; monocyte; ; amniotic fluid; ; ventricle; ; cervix;
	Top expressed in
	fetal liver hematopoietic progenitor cell; ; tibiofemoral joint; ; human fetus; ; body of femur; ; spleen; ; bone marrow; ; blood; ; tail of embryo; ; yolk sac; ; genital tubercle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	ankyrin binding; carbon dioxide transmembrane transporter activity; ammonium transmembrane transporter activity; leak channel activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	multicellular organismal iron ion homeostasis; bicarbonate transport; organic cation transport; carbon dioxide transport; erythrocyte development; cellular ion homeostasis; carbon dioxide transmembrane transport; ammonium transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	6005
	19743
	ENSG00000112077
	ENSMUSG00000023926
	Q02094
	Q9QUT0
	NM_000324
	NM_011269
	NP_000315
	NP_035399
	Wikidata
View/Edit Human	View/Edit Mouse

Rh-associated glycoprotein (RHAG) is an ammonia transporter protein that in humans is encoded by the RHAG gene.^[5]^[6] RHAG has also recently been designated CD241 (cluster of differentiation 241). Mutations in the RHAG gene can cause stomatocytosis.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112077 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023926 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matassi G, Chérif-Zahar B, Raynal V, Rouger P, Cartron JP (Jan 1998). "Organization of the human RH50A gene (RHAG) and evolution of base composition of the RH gene family". Genomics. 47 (2): 286–93. doi:10.1006/geno.1997.5112. PMID 9479501.
^ "Entrez Gene: RHAG Rh-associated glycoprotein".
^ Stewart AK, Shmukler BE, Vandorpe DH, Rivera A, Heneghan JF, Li X, Hsu A, Karpatkin M, O'Neill AF, Bauer DE, Heeney MM, John K, Kuypers FA, Gallagher PG, Lux SE, Brugnara C, Westhoff CM, Alper SL (Dec 2011). "Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S". American Journal of Physiology. Cell Physiology. 301 (6): C1325-43. doi:10.1152/ajpcell.00054.2011. PMC 3233792. PMID 21849667.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112077 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023926 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9479501-5] Matassi G, Chérif-Zahar B, Raynal V, Rouger P, Cartron JP (Jan 1998). "Organization of the human RH50A gene (RHAG) and evolution of base composition of the RH gene family". Genomics. 47 (2): 286–93. doi:10.1006/geno.1997.5112. PMID 9479501.

[entrez-6] "Entrez Gene: RHAG Rh-associated glycoprotein".

[7] Stewart AK, Shmukler BE, Vandorpe DH, Rivera A, Heneghan JF, Li X, Hsu A, Karpatkin M, O'Neill AF, Bauer DE, Heeney MM, John K, Kuypers FA, Gallagher PG, Lux SE, Brugnara C, Westhoff CM, Alper SL (Dec 2011). "Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S". American Journal of Physiology. Cell Physiology. 301 (6): C1325-43. doi:10.1152/ajpcell.00054.2011. PMC 3233792. PMID 21849667.

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