Seasonal hyperacute panuveitis

Seasonal hyperacute panuveitis (SHAPU) is an aggressive eye disease of unknown etiology, first described in 1975.[1] It has been recorded almost exclusively from Nepal, with the exception of five cases reported from Bhutan.[2] The disease affects prevalently children and can cause blindness.[3] In Nepal, it is the most common reported cause of panuveitis, and in children it is the most prevalent cause of both uveitis and panuveitis.[4]

  1. ^ Shrestha, Bharat R.; Upadhyay, Madan P. (2017). "SHAPU: Forty years on Mystery Persists". Nepalese Journal of Ophthalmology. 9 (18): 13–16. doi:10.3126/nepjoph.v9i1.17527. PMID 29022949.
  2. ^ Tamang, Sandip; Jayanna, Sushma; Tshering, Sonam Choden; Zangmo, Ugyen; Powdyel, Adwitya; Dorji, Phuntsho; Kezang, Dechen; Gurung, Kunti Devi; Dukpa, Mendu; Wangdi, Lhacha; Wangmo, Karma Yeshey; Wangmo, Dechen; Deki; Lepcha, Nor Tshering; Getshen, Kunzang; Das, Taraprasad (2023). "Seasonal Hyperacute Panuveitis (SHAPU) in Bhutan". Ocular Immunology and Inflammation: 1–7. doi:10.1080/09273948.2022.2164512. PMID 36701769. S2CID 256304512.
  3. ^ Bolakhe, Saugat (2023). "Are these moths blinding children? Nepalese researchers seek answers". Nature. doi:10.1038/d41586-023-03414-7. PMID 37923949. S2CID 265012955.
  4. ^ Karn, Mitesh; Gurung, Jamuna (2022). "Outbreak of seasonal hyperacute panuveitis disease in Nepal". The Lancet Global Health. 10 (1): e39–e40. doi:10.1016/S2214-109X(21)00513-1. PMID 34919853. S2CID 245195527.

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