Signal transducing adaptor protein

Signal transducing adaptor proteins (STAPs) are proteins that are accessory to main proteins in a signal transduction pathway.^[1] Adaptor proteins contain a variety of protein-binding modules that link protein-binding partners together and facilitate the creation of larger signaling complexes. These proteins tend to lack any intrinsic enzymatic activity themselves,^[2] instead mediating specific protein–protein interactions that drive the formation of protein complexes. Examples of adaptor proteins include MYD88,^[3]^[4] Grb2 and SHC1.

^ "Role of Signal Transducing Adaptor Protein (STAP) Family in Chronic Myelogenous Leukemia". Retrieved 24 August 2018.
^ Signal+Transducing+Adaptor+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
^ "Entrez Gene: MYD88 Myeloid differentiation primary response gene (88)".
^ Bonnert TP, Garka KE, Parnet P, Sonoda G, Testa JR, Sims JE (January 1997). "The cloning and characterization of human MyD88: a member of an IL-1 receptor related family". FEBS Letters. 402 (1): 81–4. doi:10.1016/S0014-5793(96)01506-2. PMID 9013863. S2CID 44843127.

[1] "Role of Signal Transducing Adaptor Protein (STAP) Family in Chronic Myelogenous Leukemia". Retrieved 24 August 2018.

[2] Signal+Transducing+Adaptor+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[entrez-3] "Entrez Gene: MYD88 Myeloid differentiation primary response gene (88)".

[pmid9013863-4] Bonnert TP, Garka KE, Parnet P, Sonoda G, Testa JR, Sims JE (January 1997). "The cloning and characterization of human MyD88: a member of an IL-1 receptor related family". FEBS Letters. 402 (1): 81–4. doi:10.1016/S0014-5793(96)01506-2. PMID 9013863. S2CID 44843127.

[1]

[2]

[3]

[4]