Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.[1]
As a source of the new bioengineered teeth, somatic stem cells are collected and reprogrammed to induced pluripotent stem cells which can be placed in the dental lamina directly or placed in a reabsorbable biopolymer[2] in the shape of the new tooth.[3]
- ^ Otsu, Keishi; Kumakami-Sakano, Mika; Fujiwara, Naoki; Kikuchi, Kazuko; Keller, Laetitia; Lesot, Hervé; Harada, Hidemitsu (2014). "Stem cell sources for tooth regeneration: current status and future prospects". Frontiers in Physiology. 5: 36. doi:10.3389/fphys.2014.00036. PMC 3912331. PMID 24550845.
- ^ Kellomäki, Minna; Törmälä, Pertti (2003). "Processing of Resorbable Poly-α-Hydroxy Acids for Use as Tissue-Engineering Scaffolds". Biopolymer Methods in Tissue Engineering. Vol. 238. pp. 1–10. doi:10.1385/1-59259-428-X:1. ISBN 978-1-59259-428-3.
- ^ Hill, David J. (10 May 2012). "Toothless No More - Researchers Using Stem Cells to Grow New Teeth". Singularity Hub.
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