Triazenes

Dacarbazine is a triazene used in the treatment of melanoma and Hodgkin's lymphoma.^[1]

Triazenes are organic compounds that contain the functional group R¹−N=N−NR²R³, where the R are each any of various types of substituent groups.^[2] Some anti-cancer medications and dyes are triazenes.^[3] Formally, the triazenes are related to the unstable chemical triazene, H₂N−N=NH.

^ "Dacarbazine". The American Society of Health-System Pharmacists. Archived from the original on 11 September 2017. Retrieved 8 December 2016.
^ Suleymanov, Abdusalom A.; Severin, Kay (2021-03-22). "Vinyl and Alkynyl Triazenes: Synthesis, Reactivity, and Applications". Angewandte Chemie International Edition. 60 (13): 6879–6889. doi:10.1002/anie.202011031. ISSN 1433-7851.
^ Berneth, Horst (2008). "Methine Dyes and Pigments". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a16_487.pub2. ISBN 978-3527306732.

[AHFS2016-1] "Dacarbazine". The American Society of Health-System Pharmacists. Archived from the original on 11 September 2017. Retrieved 8 December 2016.

[2] Suleymanov, Abdusalom A.; Severin, Kay (2021-03-22). "Vinyl and Alkynyl Triazenes: Synthesis, Reactivity, and Applications". Angewandte Chemie International Edition. 60 (13): 6879–6889. doi:10.1002/anie.202011031. ISSN 1433-7851.

[3] Berneth, Horst (2008). "Methine Dyes and Pigments". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a16_487.pub2. ISBN 978-3527306732.

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