U.S. Route 601 | |||||||||
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 US 601 highlighted in red | |||||||||
| Route information | |||||||||
| Auxiliary route of US 1 | |||||||||
| Length | 316.3 mi[citation needed] (509.0 km) | ||||||||
| Existed | 1927–present | ||||||||
| Major junctions | |||||||||
| South end |  US 321 near Tarboro, SC | ||||||||
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| North end |  US 52 in Mount Airy, NC | ||||||||
| Location | |||||||||
| Country | United States | ||||||||
| States | South Carolina, North Carolina | ||||||||
| Counties | SC: Jasper, Hampton, Colleton, Bamberg, Orangeburg, Calhoun, Richland, Kershaw, Lancaster, Chesterfield NC: Union, Cabarrus, Rowan, Davie, Yadkin, Surry | ||||||||
| Highway system | |||||||||
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U.S. Route 601 (US 601) is a north–south United States highway that runs for 316.3 miles (509.0 km) from U.S. Route 321, near Tarboro, South Carolina, to U.S. Route 52, in Mount Airy, North Carolina. In North Carolina, it is one of the main north-south corridors connecting the cities of Salisbury, Mocksville, and Mount Airy.
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