CDK9

CDK9
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3BLH, 3BLQ, 3BLR, 3LQ5, 3MI9, 3MIA, 3MY1, 3TN8, 3TNH, 3TNI, 4BCF, 4BCG, 4BCH, 4BCI, 4BCJ, 4EC8, 4EC9, 4IMY, 4OGR, 4OR5
Dynodwyr
Cyfenwau	CDK9, C-2k, CDC2L4, CTK1, PITALRE, TAK, cyclin-dependent kinase 9, cyclin dependent kinase 9
Dynodwyr allanol	OMIM: 603251 HomoloGene: 55566 GeneCards: CDK9
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • transferase activity; • protein kinase activity; • 7SK snRNA binding; • transcription coactivator binding; • snRNA binding; • ATP binding; • RNA polymerase II core promoter sequence-specific DNA binding; • DNA binding; • transcription factor binding; • GO:0001948, GO:0016582 protein binding; • protein serine/threonine kinase activity; • chromatin binding; • kinase activity; • cyclin-dependent protein serine/threonine kinase activity; • RNA polymerase II CTD heptapeptide repeat kinase activity; • protein kinase binding; • cyclin binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cydrannau o'r gell	• cytoplasm; • cnewyllyn cell; • bilen; • nucleoplasm; • transcription elongation factor complex; • cyclin/CDK positive transcription elongation factor complex; • PML body; • Cromosom; • cytoplasmic ribonucleoprotein granule; • cyclin-dependent protein kinase holoenzyme complex;
Prosesau biolegol	• positive regulation of cardiac muscle hypertrophy; • positive regulation of mRNA 3'-UTR binding; • regulation of muscle cell differentiation; • negative regulation of mRNA polyadenylation; • GO:0100026 DNA repair; • cellular response to cytokine stimulus; • positive regulation of viral transcription; • replication fork processing; • protein phosphorylation; • GO:0033127, GO:2000281, GO:2000817 regulation of histone modification; • regulation of mitotic cell cycle; • cellular response to DNA damage stimulus; • transcription initiation from RNA polymerase II promoter; • regulation of DNA repair; • GO:0009373 regulation of transcription, DNA-templated; • cell population proliferation; • transcription by RNA polymerase II; • phosphorylation; • positive regulation of histone H2B ubiquitination; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • transcription, DNA-templated; • snRNA transcription by RNA polymerase II; • transcription elongation from RNA polymerase II promoter; • phosphorylation of RNA polymerase II C-terminal domain; • positive regulation of transcription elongation from RNA polymerase II promoter;
	Sources:Amigo / QuickGO
Orthologau
	1025
	n/a
	ENSG00000136807
	n/a
	P50750
	n/a
	NM_001261
	n/a
	NP_001252; NP_001252.1
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDK9 yw CDK9 a elwir hefyd yn Cyclin-dependent kinase 9 (CDC2-related kinase), isoform CRA_a a Cyclin dependent kinase 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q34.11.^[2]

[1] "Human PubMed Reference:".

[2] CDK9 - Cronfa NCBI

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