CYP2D6

CYP2D6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2F9Q, 3QM4, 3TBG, 3TDA, 4WNT, 4WNU, 4WNV, 4WNW, 4XRY, 4XRZ
Dynodwyr
Cyfenwau	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1, cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 2D6
Dynodwyr allanol	OMIM: 124030 HomoloGene: 133550 GeneCards: CYP2D6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • iron ion binding • metal ion binding • heme binding • GO:0050602 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • oxidoreductase activity • aromatase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • steroid hydroxylase activity • monooxygenase activity Cydrannau o'r gell • organelle membrane • endoplasmic reticulum membrane • bilen • intracellular membrane-bounded organelle • Reticwlwm endoplasmig • mitocondria • cytoplasm Prosesau biolegol • steroid metabolic process • alkaloid metabolic process • coumarin metabolic process • lipid metabolism • isoquinoline alkaloid metabolic process • GO:1900774, GO:1900783, GO:1900795, GO:1901084, GO:1900780, GO:1900777, GO:1900771, GO:1901014, GO:1902180, GO:1900987, GO:1900990 alkaloid catabolic process • oxidative demethylation • heterocycle metabolic process • negative regulation of binding • monoterpenoid metabolic process • xenobiotic metabolic process • arachidonic acid metabolic process • negative regulation of cellular organofluorine metabolic process • long-chain fatty acid biosynthetic process • organic acid metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1565	n/a
Ensembl	ENSG00000100197 ENSG00000275211 ENSG00000280905 ENSG00000282966 ENSG00000283284 ENSG00000272532	n/a
UniProt	P10635	n/a
RefSeq (mRNA)	NM_000106 NM_001025161	n/a
RefSeq (protein)	NP_000097 NP_001020332	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYP2D6 yw CYP2D6 a elwir hefyd yn Cytochrome P450 family 2 subfamily D member 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q13.2.^[2]

1. ↑ "Human PubMed Reference:".
2. ↑ CYP2D6 - Cronfa NCBI