N-Myc

MYCN
識別子
記号	MYCN, MODED, N-myc, NMYC, ODED, bHLHe37, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, MYCN proto-oncogene, bHLH transcription factor, MYCNsORF, MYCNsPEP
外部ID	OMIM: 164840 MGI: 97357 HomoloGene: 3922 GeneCards: MYCN
遺伝子の位置 (ヒト)
染色体	2番染色体 (ヒト)
終点	15,947,007 bp
遺伝子の位置 (マウス)
染色体	12番染色体 (マウス)
終点	12,991,915 bp
RNA発現パターン
	; ; ; ;
	さらなる参照発現データ
遺伝子オントロジー
分子機能	• DNA結合; • protein dimerization activity; • DNA-binding transcription factor activity; • 血漿タンパク結合; • RNA polymerase II cis-regulatory region sequence-specific DNA binding; • DNA-binding transcription activator activity, RNA polymerase II-specific; • キナーゼ結合; • DNA-binding transcription factor activity, RNA polymerase II-specific;
細胞の構成要素	• クロマチン; • 細胞核; • 核小体;
生物学的プロセス	• regulation of transcription, DNA-templated; • regulation of transcription by RNA polymerase II; • transcription, DNA-templated; • positive regulation of gene expression; • 遺伝子発現の負の調節; • positive regulation of production of miRNAs involved in gene silencing by miRNA; • transcription by RNA polymerase II; • cartilage condensation; • positive regulation of mesenchymal cell proliferation; • positive regulation of cell population proliferation; • positive regulation of cell death; • 肺発生; • embryonic digit morphogenesis; • regulation of inner ear auditory receptor cell differentiation; • positive regulation of transcription, DNA-templated; • positive regulation of transcription by RNA polymerase II; • embryonic skeletal system morphogenesis; • negative regulation of astrocyte differentiation; • branching morphogenesis of an epithelial tube; • negative regulation of reactive oxygen species metabolic process;
	出典:Amigo / QuickGO
オルソログ
	4613
	18109
	ENSG00000134323
	ENSMUSG00000037169
	P04198
	P03966
	NM_005378; NM_001293228; NM_001293231; NM_001293233
	NM_008709
	NP_001280157; NP_001280160; NP_001280162; NP_005369
	NP_032735
	ウィキデータ
閲覧/編集ヒト	閲覧/編集マウス

N-Mycは、ヒトではMYCN遺伝子にコードされるタンパク質である。bHLHe37（class E basic helix-loop-helix protein 37）としても知られる。

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000134323 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037169 - Ensembl, May 2017
^ Human PubMed Reference:
^ Mouse PubMed Reference:

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000134323 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037169 - Ensembl, May 2017

[3] Human PubMed Reference:

[4] Mouse PubMed Reference:

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