Plazmin

PLG
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 1B2I, 1BML, 1BUI, 1CEA, 1CEB, 1DDJ, 1HPJ, 1HPK, 1I5K, 1KI0, 1KRN, 1L4D, 1L4Z, 1PK4, 1PKR, 1PMK, 1QRZ, 1RJX, 2DOH, 2DOI, 2KNF, 2L0S, 2PK4, 3UIR, 4A5T, 4CIK, 4DCB, 4DUR, 4DUU, 5HPG
Identifikatori
Aliasi	PLG
Vanjski ID-jevi	OMIM: 173350 MGI: 97620 HomoloGene: 55452 GeneCards: PLG
Lokacija gena (čovjek) Hrom. Hromosom 6 (čovjek)[1] Bend 6q26 Početak 160,702,238 bp[1] Kraj 160,754,097 bp[1]
Lokacija gena (miš) Hrom. Hromosom 17 (miš)[2] Bend 17 A1|17 8.5 cM Početak 12,597,495 bp[2] Kraj 12,638,272 bp[2]
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • apolipoprotein binding • protein domain specific binding • GO:0070122 peptidase activity • GO:0001948, GO:0016582 vezivanje za proteine • serine-type peptidase activity • signaling receptor binding • hydrolase activity • serine-type endopeptidase activity • chaperone binding • proteasome core complex binding • protein antigen binding • endopeptidase activity • vezivanje enzima • kinase binding Ćelijska komponenta • blood microparticle • extracellular region • cell surface • extrinsic component of external side of plasma membrane • Egzosom • platelet alpha granule lumen • Vanćelijsko • ćelijska membrana • extrinsic component of plasma membrane • intracellular membrane-bounded organelle • collagen-containing extracellular matrix Biološki proces • Hemostaza • negative regulation of cell-substrate adhesion • negative regulation of fibrinolysis • negative regulation of cell-cell adhesion mediated by cadherin • platelet degranulation • extracellular matrix disassembly • positive regulation of fibrinolysis • tissue remodeling • negative regulation of cell population proliferation • Koagulacija (krv) • Proteoliza • Fibrinoliza • positive regulation of blood vessel endothelial cell migration • tissue regeneration • myoblast differentiation • muscle cell cellular homeostasis • proteolysis involved in cellular protein catabolic process • trophoblast giant cell differentiation • labyrinthine layer blood vessel development • mononuclear cell migration Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	5340	18815
Ensembl	ENSG00000122194	ENSMUSG00000059481
UniProt	P00747	P20918
RefSeq (mRNK)	NM_001168338 NM_000301	NM_008877
RefSeq (bjelančevina)	NP_000292 NP_001161810	NP_032903
Lokacija (UCSC)	Chr 6: 160.7 – 160.75 Mb	Chr 17: 12.6 – 12.64 Mb
PubMed pretraga	[3]	[4]
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Plazmin, sa svojim prekursorom zvamim plazminogen, jest značajan enzim (EC: 3.4.21.7) u krvi, koji razlaže mnoge plazmatske proteine, uključujući i fibrin krvnih pločica. Razgradnja fibrina naziva se fibrinoliza. Kod ljudi kodiran je genom PLG.^[5]

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000122194 - Ensembl, maj 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000059481 - Ensembl, maj 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: plasminogen".