1-Deoxynojirimycin

1-Deoxynojirimycin
Names
	Preferred IUPAC name (2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol
Identifiers
CAS Number	19130-96-2 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:44369;
ChemSpider	27360;
ECHA InfoCard	100.119.812
IUPHAR/BPS	4642;
KEGG	D09605;
PubChem CID	29435;
UNII	FZ56898FLE ;
CompTox Dashboard (EPA)	DTXSID70172647 ;
	InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1 Key: LXBIFEVIBLOUGU-JGWLITMVSA-N;
	SMILES C1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O;
Properties
Chemical formula	C6H13NO4
Molar mass	163.173 g·mol−1
Melting point	195 °C (383 °F; 468 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

1-Deoxynojirimycin (DNJ or 1-DNJ), also called duvoglustat or moranolin,^[1] is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ,^[2] and on alternate routes of production, such as via Bacillus species.^[3]

^ KEGG: Deoxynojirimycin.
^ Chaluntorn Vichasilp; et al. (2012). "Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction". LWT - Food Science and Technology. 45 (2): 226–232. doi:10.1016/j.lwt.2011.09.008.
^ Onose, S; Ikeda, R; Nakagawa, K; Kimura, T; Yamagishi, K; Higuchi, O; Miyazawa, T (2013). "Production of the α-glycosidase inhibitor 1-deoxynojirimycin from Bacillus species". Food Chemistry. 138 (1): 516–23. doi:10.1016/j.foodchem.2012.11.012. PMID 23265519.

[1] KEGG: Deoxynojirimycin.

[2] Chaluntorn Vichasilp; et al. (2012). "Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction". LWT - Food Science and Technology. 45 (2): 226–232. doi:10.1016/j.lwt.2011.09.008.

[3] Onose, S; Ikeda, R; Nakagawa, K; Kimura, T; Yamagishi, K; Higuchi, O; Miyazawa, T (2013). "Production of the α-glycosidase inhibitor 1-deoxynojirimycin from Bacillus species". Food Chemistry. 138 (1): 516–23. doi:10.1016/j.foodchem.2012.11.012. PMID 23265519.

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