| Duration | Group stage plus three knockout rounds |
|---|---|
| Number of teams | 16 |
| Broadcast partners | BBC Sport |
| Winners | St Helens |
| Runners-up | Leeds Rhinos |
| Biggest home win | Leeds Rhinos 92–0 Leigh Miners Rangers (3 April 2022) |
| Biggest away win | Hull FC 0–114 Huddersfield Giants (3 April 2022) |
The 2022 Women's Challenge Cup (sponsored as the 2022 Betfred Women's Challenge Cup) was the 10th staging of the Rugby Football League's cup competition for women's rugby league clubs. The competition was won by St Helens who beat Leeds Rhinos 18–8 in the final at Elland Road on 7 May.
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