Back MDA Bulgarian 3,4-methylendioxyamfetamin Czech 3,4-metylendioksyamfetamin Danish 3,4-Methylendioxyamphetamin German MDA (drogo) Esperanto 3,4-metilendioxianfetamina Spanish 3,4-metyleenidioksiamfetamiini Finnish 3,4-Méthylènedioxyamphétamine French Metilenedioxianfetamina Galician MDA (chimica) Italian

3,4-Methylenedioxyamphetamine

Methylenedioxyamphetamine
INN: Tenamfetamine
Clinical data
Other namesMDA; Tenamfetamine; Amphedoxamine; Sally; Sassafras; Sass-a-frass; Sass; Mellow Drug of America; Hug drug; Love; 3,4-Methylenedioxy-α-methylphenethylamine; 5-(2-Aminopropyl)-1,3-benzodioxole; EA-1298; NSC-9978; NSC-27106; SKF-5
Routes of
administration		By mouth, sublingual, insufflation, intravenous
Drug classEntactogen; Stimulant; Psychedelic; Serotonin–norepinephrine–dopamine releasing agent; Serotonin 5-HT2 receptor agonist
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
MetabolismHepatic (CYP extensively involved)
Elimination half-life10.9 hours[2]
Duration of action6–8 hours[2]
ExcretionRenal
Identifiers
  • 1-(2H-1,3-Benzodioxol-5-yl)propan-2-amine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.230.706 Edit this at Wikidata
Chemical and physical data
FormulaC10H13NO2
Molar mass179.219 g·mol−1
3D model (JSmol)
  • NC(C)CC1=CC2=C(C=C1)OCO2
  • InChI=1S/C10H13NO2/c1-7(11)4-8-2-3-9-10(5-8)13-6-12-9/h2-3,5,7H,4,6,11H2,1H3 checkY
  • Key:NGBBVGZWCFBOGO-UHFFFAOYSA-N checkY
  (verify)

3,4-Methylenedioxyamphetamine (MDA) is an entactogen, stimulant, and psychedelic drug of the amphetamine and MDxx families that is encountered mainly as a recreational drug.[3] In its pharmacology, MDA is a serotonin–norepinephrine–dopamine releasing agent (SNDRA). In most countries, the drug is a controlled substance and its possession and sale are illegal.

MDA is rarely sought as a recreational drug compared to other amphetamines; however, it remains widely used due to it being a primary metabolite,[4] the product of hepatic N-dealkylation,[5] of MDMA. It is also a common adulterant of illicitly produced MDMA.[6][7]

  1. ^ "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Brazilian Health Regulatory Agency (in Brazilian Portuguese). Diário Oficial da União (published 25 July 2023). 24 July 2023. Archived from the original on 27 August 2023. Retrieved 27 August 2023.
  2. ^ a b Cite error: The named reference BaggottGarrisonCoyle2019 was invoked but never defined (see the help page).
  3. ^ Alexander T. Shulgin, Ann Shulgin (1991). "#100 MDA 3,4-METHYLENEDIOXYAMPHETAMINE". PiHKAL: A Chemical Love Story (1st ed.). Berkeley, CA: Transform Press. pp. 714–719. ISBN 978-0-9630096-0-9. OCLC 25627628.
  4. ^ Crean RD, Davis SA, Von Huben SN, Lay CC, Katner SN, Taffe MA (October 2006). "Effects of (+/-)3,4-methylenedioxymethamphetamine, (+/-)3,4-methylenedioxyamphetamine and methamphetamine on temperature and activity in rhesus macaques". Neuroscience. 142 (2): 515–525. doi:10.1016/j.neuroscience.2006.06.033. PMC 1853374. PMID 16876329.
  5. ^ de la Torre R, Farré M, Roset PN, Pizarro N, Abanades S, Segura M, et al. (April 2004). "Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition". Therapeutic Drug Monitoring. 26 (2): 137–144. doi:10.1097/00007691-200404000-00009. PMID 15228154.
  6. ^ "EcstasyData.org: Test Result Statistics: Substances by Year". EcstasyData.org. Retrieved 27 June 2017.
  7. ^ "Trans European Drug Information". idpc.net. Archived from the original on 4 November 2021. Retrieved 27 June 2017.

Rich TVX News Network Site

Rich TVX News Network Info

© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search