Adolfo J. de Bold

Adolfo J. de Bold
Born
Adolfo José de Bold

(1942-02-14)February 14, 1942
DiedOctober 22, 2021(2021-10-22) (aged 79)
Known forAtrial natriuretic peptide (ANP) discovery and synthesis; endocrine functions of the heart
Scientific career
FieldsCardiac research

Adolfo José de Bold OC FRSC (February 14, 1942 – October 22, 2021) was an Argentine-born Canadian cardiovascular researcher, best known for his discovery of atrial natriuretic peptide (ANP), a polypeptide hormone secreted by heart muscle cells. The hormone plays a role in regulating blood pressure, blood volume, and cardiovascular growth, and its discovery proved the endocrine function of the heart.

De Bold was an officer of the Order of Canada and was an inductee into the Canadian Medical Hall of Fame.


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