Back مستقبلات ألفا-2 الأدرينالية Arabic Α2-Adrenozeptor German Receptor adrenérgico alfa 2 Spanish Receptorium adrenergicum alpha 2 Latin Receptor adrenérgico alfa 2 Portuguese Alfa-2 adrenergički receptor Serbo-Croatian Alfa-2 adrenergički receptor Serbian

Alpha-2 adrenergic receptor

See also: Adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists of three highly homologous subtypes, including α2A-, α2B-, and α2C-adrenergic. Some species other than humans express a fourth α2D-adrenergic receptor as well.[1] Catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) signal through the α2-adrenergic receptor in the central and peripheral nervous systems.

  1. ^ Ruuskanen JO, Xhaard H, Marjamäki A, Salaneck E, Salminen T, Yan YL, Postlethwait JH, Johnson MS, Larhammar D, Scheinin M (January 2004). "Identification of duplicated fourth alpha2-adrenergic receptor subtype by cloning and mapping of five receptor genes in zebrafish". Molecular Biology and Evolution. 21 (1): 14–28. doi:10.1093/molbev/msg224. PMID 12949138.

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