Antibody microarray

An antibody microarray (also known as antibody array) is a specific form of protein microarray. In this technology, a collection of captured antibodies are spotted and fixed on a solid surface such as glass, plastic, membrane, or silicon chip, and the interaction between the antibody and its target antigen is detected. Antibody microarrays are often used for detecting protein expression from various biofluids including serum, plasma and cell or tissue lysates. Antibody arrays may be used for both basic research and medical and diagnostic applications.^[1]^[2]^[3]^[4]

^ Rivas LA, García-Villadangos M, Moreno-Paz M, Cruz-Gil P, Gómez-Elvira J, Parro V (November 2008). "A 200-antibody microarray biochip for environmental monitoring: searching for universal microbial biomarkers through immunoprofiling". Anal. Chem. 80 (21): 7970–9. doi:10.1021/ac8008093. PMID 18837515.
^ Chaga GS (2008). "Antibody Arrays for Determination of Relative Protein Abundances". Tissue Proteomics. Methods in Molecular Biology. Vol. 441. pp. 129–51. doi:10.1007/978-1-60327-047-2_9. ISBN 978-1-58829-679-5. PMID 18370316.
^ Wilson J. J.; Burgess R.; Mao Y. Q.; Luo S.; Tang H.; Jones V. S.; et al. (2015). "Chapter Seven-Antibody Arrays in Biomarker Discovery". Advances in Clinical Chemistry. Vol. 69. pp. 255–324. doi:10.1016/bs.acc.2015.01.002. ISBN 9780128022658. PMID 25934364.
^ Lin Y., Huang R.C., Cao X., Wang S.-M., Shi Q., Huang R.-P. (2003). "Detection of multiple cytokines by protein arrays from cell lysate and tissue lysate". Clin Chem Lab Med. 41 (2): 139–145. doi:10.1515/cclm.2003.023. PMID 12666998. S2CID 34616684.{{cite journal}}: CS1 maint: multiple names: authors list (link)

[pmid18837515-1] Rivas LA, García-Villadangos M, Moreno-Paz M, Cruz-Gil P, Gómez-Elvira J, Parro V (November 2008). "A 200-antibody microarray biochip for environmental monitoring: searching for universal microbial biomarkers through immunoprofiling". Anal. Chem. 80 (21): 7970–9. doi:10.1021/ac8008093. PMID 18837515.

[pmid18370316-2] Chaga GS (2008). "Antibody Arrays for Determination of Relative Protein Abundances". Tissue Proteomics. Methods in Molecular Biology. Vol. 441. pp. 129–51. doi:10.1007/978-1-60327-047-2_9. ISBN 978-1-58829-679-5. PMID 18370316.

[3] Wilson J. J.; Burgess R.; Mao Y. Q.; Luo S.; Tang H.; Jones V. S.; et al. (2015). "Chapter Seven-Antibody Arrays in Biomarker Discovery". Advances in Clinical Chemistry. Vol. 69. pp. 255–324. doi:10.1016/bs.acc.2015.01.002. ISBN 9780128022658. PMID 25934364.

[4] Lin Y., Huang R.C., Cao X., Wang S.-M., Shi Q., Huang R.-P. (2003). "Detection of multiple cytokines by protein arrays from cell lysate and tissue lysate". Clin Chem Lab Med. 41 (2): 139–145. doi:10.1515/cclm.2003.023. PMID 12666998. S2CID 34616684.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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