Back Cowa kacipinang ko kaadada AMI ناقل عديم الأعراض Arabic Douger yac'h Breton Portador asimptomàtic Catalan Bacilonosič Czech Asymptomatisk bærer Danish Dauerausscheider German Ασυμπτωματικός φορέας Greek Eramaile osasuntsu Basque ناقل بیماری Persian

Asymptomatic carrier

Typhoid Mary in a 1909 newspaper illustration. Mary Mallon was an asymptomatic carrier of Salmonella typhi who is thought to have infected 53 others with typhoid fever while continuing her work as a cook.

An asymptomatic carrier is a person or other organism that has become infected with a pathogen, but shows no signs or symptoms.[1]

Although unaffected by the pathogen, carriers can transmit it to others or develop symptoms in later stages of the disease. Asymptomatic carriers play a critical role in the transmission of common infectious diseases such as typhoid, HIV, C. difficile, influenzas, cholera, tuberculosis, and COVID-19,[2] although the latter is often associated with "robust T-cell immunity" in more than a quarter of patients studied.[3] While the mechanism of disease-carrying is still unknown, researchers have made progress towards understanding how certain pathogens can remain dormant in a human for a period of time.[4] A better understanding of asymptomatic disease carriers is crucial to the fields of medicine and public health as they work towards mitigating the spread of common infectious diseases.

  1. ^ "Dictionary Definition". Medical-dictionary.thefreedictionary.com. Retrieved 20 August 2013.
  2. ^ Lai, Chih-Cheng; Liu, Yen Hung; Wang, Cheng-Yi; Wang, Ya-Hui; Hsueh, Shun-Chung; Yen, Muh-Yen; Ko, Wen-Chien; Hsueh, Po-Ren (2020-03-04). "Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths". Journal of Microbiology, Immunology and Infection. 53 (3): 404–412. doi:10.1016/j.jmii.2020.02.012. ISSN 1684-1182. PMC 7128959. PMID 32173241.
  3. ^ Sekine, Takuya; Perez-Potti, André; Rivera-Ballesteros, Olga; Strålin, Kristoffer; Gorin, Jean-Baptiste; Olsson, Annika; Llewellyn-Lacey, Sian; Kamal, Habiba; Bogdanovic, Gordana; Muschiol, Sandra; Wullimann, David J.; Kammann, Tobias; Emgård, Johanna; Parrot, Tiphaine; Folkesson, Elin; Rooyackers, Olav; Eriksson, Lars I.; Henter, Jan-Inge; Sönnerborg, Anders; Allander, Tobias; Albert, Jan; Nielsen, Morten; Klingström, Jonas; Gredmark-Russ, Sara; Björkström, Niklas K.; Sandberg, Johan K.; Price, David A.; Ljunggren, Hans-Gustaf; Aleman, Soo; Buggert, Marcus (2020). "Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19". Cell. 183 (1): 158–168.e14. doi:10.1016/j.cell.2020.08.017. PMC 7427556. PMID 32979941.
  4. ^ "Denise M. Monack". WikiGenes. Retrieved 2016-02-14.

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