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Original author(s) | Stephen Altschul, Warren Gish, Webb Miller, Eugene Myers, and David Lipman |
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Developer(s) | NCBI |
Stable release | 2.16.0+[1]
/ 25 June 2024 |
Written in | C and C++[2] |
Operating system | UNIX, Linux, Mac, MS-Windows |
Type | Bioinformatics tool |
License | Public domain |
Website | blast |
In bioinformatics, BLAST (basic local alignment search tool)[3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. A BLAST search enables a researcher to compare a subject protein or nucleotide sequence (called a query) with a library or database of sequences, and identify database sequences that resemble the query sequence above a certain threshold. For example, following the discovery of a previously unknown gene in the mouse, a scientist will typically perform a BLAST search of the human genome to see if humans carry a similar gene; BLAST will identify sequences in the human genome that resemble the mouse gene based on similarity of sequence.
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