BMX (gene)

BMX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EKX, 2YS2, 3SXR, 3SXS
Identifiers
Aliases	BMX, ETK, PSCTK2, PSCTK3, BMX non-receptor tyrosine kinase
External IDs	OMIM: 300101; MGI: 1101778; HomoloGene: 20411; GeneCards: BMX; OMA:BMX - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	15,556,529 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	163,041,189 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; right auricle; ; bone marrow; ; cardiac muscle tissue of right atrium; ; testicle; ; right coronary artery; ; subcutaneous adipose tissue; ; right lung; ; Achilles tendon; ; urethra;
	Top expressed in
	granulocyte; ; atrioventricular valve; ; atrium; ; lumbar spinal ganglion; ; tunica media of zone of aorta; ; zygote; ; tibiofemoral joint; ; endocardial cushion; ; right lung lobe; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; signal transducer activity; metal ion binding; kinase activity; protein binding; protein tyrosine kinase activity; signaling receptor binding; ATP binding; non-membrane spanning protein tyrosine kinase activity;
Cellular component	cytoplasm; cytosol; extrinsic component of cytoplasmic side of plasma membrane; ruffle membrane; nucleoplasm; plasma membrane;
Biological process	intracellular signal transduction; phosphorylation; NK T cell differentiation; transmembrane receptor protein tyrosine kinase signaling pathway; protein phosphorylation; cell adhesion; regulation of cell population proliferation; peptidyl-tyrosine autophosphorylation; protein autophosphorylation; mesoderm development; innate immune response; signal transduction; apoptotic process; phosphatidylinositol biosynthetic process; adaptive immune response; B cell receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	660
	12169
	ENSG00000102010
	ENSMUSG00000031377
	P51813
	P97504
	NM_001721; NM_203281; NM_001320866
	NM_009759
	NP_001307795; NP_001712; NP_975010
	NP_033889
	Wikidata
View/Edit Human	View/Edit Mouse

Cytoplasmic tyrosine-protein kinase BMX is an enzyme that in humans is encoded by the BMX gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102010 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031377 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K (December 1994). "BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2". Oncogene. 9 (12): 3683–8. PMID 7970727.
^ "Entrez Gene: BMX BMX non-receptor tyrosine kinase".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000102010 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031377 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7970727-5] Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K (December 1994). "BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2". Oncogene. 9 (12): 3683–8. PMID 7970727.

[entrez-6] "Entrez Gene: BMX BMX non-receptor tyrosine kinase".

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