Binding selectivity

In chemistry, binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex. Binding selectivity describes how a ligand may bind more preferentially to one receptor than another. A selectivity coefficient is the equilibrium constant for the reaction of displacement by one ligand of another ligand in a complex with the substrate. Binding selectivity is of major importance in biochemistry[1] and in chemical separation processes.

  1. ^ Klotz, I.M. (1997). Ligand-Receptor Energetics: A Guide for the Perplexed. Wiley. ISBN 978-0-471-17626-8.

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