Biological functions of nitric oxide

Biological functions of nitric oxide are roles that nitric oxide plays within biology.

Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of NO. In mammals including humans, nitric oxide is a signaling molecule involved in several physiological and pathological processes.[1] It is a powerful vasodilator with a half-life of a few seconds in the blood. Standard pharmaceuticals such as nitroglycerine and amyl nitrite are precursors to nitric oxide. Low levels of nitric oxide production are typically due to ischemic damage in the liver.

As a consequence of its importance in neuroscience, physiology, and immunology, nitric oxide was proclaimed "Molecule of the Year" in 1992.[2] Research into its function led to the 1998 Nobel Prize for elucidating the role of nitric oxide as a cardiovascular signalling molecule.

  1. ^ Culotta E, Koshland DE (December 1992). "NO news is good news". Science. 258 (5090): 1862–1865. Bibcode:1992Sci...258.1862C. doi:10.1126/science.1361684. PMID 1361684.

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