Bovine serum albumin

albumin
Identifiers
Organism	Bos taurus (domestic cow)
Symbol	ALB
Entrez	280717
HomoloGene	105925
RefSeq (mRNA)	NM_180992
RefSeq (Prot)	NP_851335
UniProt	P02769
Other data
Chromosome	6: 91.54 - 91.57 Mb
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Bovine serum albumin (BSA or "Fraction V") is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments.

The nickname "Fraction V" refers to albumin being the fifth fraction of the original Edwin Cohn purification methodology that made use of differential solubility characteristics of plasma proteins. By manipulating solvent concentrations, pH, salt levels, and temperature, Cohn was able to pull out successive "fractions" of blood plasma. The process was first commercialized with human albumin for medical use and later adopted for production of BSA.