CYP3A5

CYP3A5
Identifiers
Aliases	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3, cytochrome P450 family 3 subfamily A member 5
External IDs	OMIM: 605325; MGI: 106099; HomoloGene: 133568; GeneCards: CYP3A5; OMA:CYP3A5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	99,679,998 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	145,406,533 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; right lobe of liver; ; gallbladder; ; duodenum; ; rectum; ; mucosa of sigmoid colon; ; body of pancreas; ; buccal mucosa cell; ; pylorus; ; mucosa of transverse colon;
	Top expressed in
	hepatobiliary system; ; liver; ; sexually immature organism; ; duodenum; ; muscle; ; human fetus; ; sensory nervous system; ; sensory organ; ; retina; ; muscle tissue;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	iron ion binding; oxidoreductase activity; oxygen binding; aromatase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; metal ion binding; monooxygenase activity; estrogen 16-alpha-hydroxylase activity;
Cellular component	organelle membrane; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; endoplasmic reticulum; membrane;
Biological process	xenobiotic metabolic process; alkaloid catabolic process; oxidative demethylation; lipid hydroxylation; steroid metabolic process; estrogen metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1577
	13114
	ENSG00000106258
	ENSMUSG00000038656
	P20815
	Q64481
	NM_000777; NM_001190484; NM_001291829; NM_001291830
	NM_007820
	NP_000768; NP_001177413; NP_001278758; NP_001278759
	NP_031846
	Wikidata
View/Edit Human	View/Edit Mouse

Cytochrome P450 3A5 is a protein that in humans is encoded by the CYP3A5 gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106258 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038656 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106258 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038656 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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