Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel,[1] which are a type of calcium channel regulated by changes in membrane potential. Some calcium channels are regulated by the binding of a ligand.[2][3] Other calcium channels can also be regulated by both voltage and ligands to provide precise control over ion flow. Some cation channels allow calcium as well as other cations to pass through the membrane.

Calcium channels can participate in the creation of action potentials across cell membranes. Calcium channels can also be used to release calcium ions as second messengers within the cell, affecting downstream signaling pathways.    

  1. ^ "calcium channel" at Dorland's Medical Dictionary
  2. ^ Striggow F, Ehrlich BE (August 1996). "Ligand-gated calcium channels inside and out". Current Opinion in Cell Biology. 8 (4): 490–495. doi:10.1016/S0955-0674(96)80025-1. PMID 8791458.
  3. ^ Zamponi, Gerald W. (2017-12-20). "A Crash Course in Calcium Channels". ACS Chemical Neuroscience. 8 (12): 2583–2585. doi:10.1021/acschemneuro.7b00415. ISSN 1948-7193. PMID 29131938.

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