Cancer

Cancer
Other namesMalignant tumor, malignant neoplasm
A coronal CT scan showing a malignant mesothelioma
Legend: → tumor ←, ✱ central pleural effusion, 1 & 3 lungs, 2 spine, 4 ribs, 5 aorta, 6 spleen, 7 & 8 kidneys, 9 liver
Pronunciation
SpecialtyOncology
SymptomsLump, abnormal bleeding, prolonged cough, unexplained weight loss, change in bowel movements[1]
Risk factorsExposure to carcinogens, tobacco, obesity, poor diet, lack of physical activity, excessive alcohol, certain infections[2][3]
TreatmentRadiation therapy, surgery, chemotherapy, targeted therapy[2][4]
PrognosisAverage five-year survival 66% (USA)[5]
Frequency24 million annually (2019)[6]
Deaths10 million annually (2019)[6]

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.[2][7] These contrast with benign tumors, which do not spread.[7] Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements.[1] While these symptoms may indicate cancer, they can also have other causes.[1] Over 100 types of cancers affect humans.[7]

  1. ^ a b c "Cancer – Signs and symptoms". NHS Choices. Archived from the original on 8 June 2014. Retrieved 10 June 2014.
  2. ^ a b c Cite error: The named reference WHO2018 was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Enviro2008 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference TCT2018 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Seer2014 was invoked but never defined (see the help page).
  6. ^ a b Kocarnik JM, Compton K, Dean FE, Fu W, Gaw BL, Harvey JD, et al. (March 2022). "Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019". JAMA Oncology. 8 (3): 420–444. doi:10.1001/jamaoncol.2021.6987. ISSN 2374-2437. PMC 8719276. PMID 34967848.
  7. ^ a b c "Defining Cancer". National Cancer Institute. 17 September 2007. Retrieved 28 March 2018.

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