Charles Curtis (1860–1936) was the 31st vice president of the United States.
Charles Curtis may also refer to:
- Charles Curtis (botanist) (1853–1928), English plant-collector
- Charles Curtis (musician), avant-garde American musician
- Charles Curtis (storekeeper) (1850–1923), New Zealand storekeeper and local politician
- Charles B. Curtis (born 1940), former chairman of the Federal Energy Regulatory Commission
- Charles Berwick Curtis (1795–1876), manufacturer of gunpowder
- Charles David Curtis (born 1939), British geologist
- Charles Gordon Curtis (1860–1953), American engineer, turbine inventor, winner of the Rumford Prize
- Charles W. Curtis (born 1926), mathematician
- Chuck Curtis (1935–2016), American football coach
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