Cholera toxin

Cholera toxin mechanism

Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is an AB5 multimeric protein complex secreted by the bacterium Vibrio cholerae.[1][2] CTX is responsible for the massive, watery diarrhea characteristic of cholera infection.[3] It is a member of the heat-labile enterotoxin family.

  1. ^ Ryan KJ; Ray CG, eds. (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. p. 375. ISBN 978-0-8385-8529-0.
  2. ^ Faruque, Shah M; Nair, G. Balakrish, eds. (July 2008). Vibrio cholerae: Genomics and Molecular Biology. Caister Academic Press. ISBN 978-1-904455-33-2.
  3. ^ Aizpurua-Olaizola, Oier; Sastre Torano, Javier; Pukin, Aliaksei; Fu, Ou; Boons, Geert Jan; de Jong, Gerhardus J.; Pieters, Roland J. (2018). "Affinity capillary electrophoresis for the assessment of binding affinity of carbohydrate-based cholera toxin inhibitors". Electrophoresis. 39 (2): 344–347. doi:10.1002/elps.201700207. ISSN 1522-2683. PMID 28905402. S2CID 33657660.

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