Back التهاب البنكرياس المزمن Arabic Xroniki pankreatit Azerbaijani Pancreatitis crònica Catalan Pankreatitis#Chronische Pankreatitis German Χρόνια παγκρεατίτιδα Greek Pancreatitis crónica Spanish Pankreatitis kroniko Basque Krooninen haimatulehdus Finnish Pancréatite chronique French דלקת לבלב כרונית HE

Chronic pancreatitis

Chronic pancreatitis
Other namesPancreatitis – chronic – discharge[1]
Axial CT showing multiple calcifications in the pancreas in a patient with chronic pancreatitis
SpecialtyGastroenterology Edit this on Wikidata
SymptomsNausea and vomiting[2][3]
ComplicationsExocrine pancreatic insufficiency, Endocrine pancreatic insufficiency (Type 3c diabetes), pancreatic pseudocyst,[4] pancreatic cancer,[4] vitamin deficiency (fat-soluble vitamins)[4]
CausesAlcohol(ism), Immune disorder[5]
Diagnostic methodSerum trypsinogen, Fecal fat test[2]
TreatmentPain medicines, avoiding alcohol(and smoking), among other possible management efforts[2]
Frequency50 per 100,000 persons (prevalence)

Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions.[1] It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption. It is a disease process characterized by irreversible damage to the pancreas as distinct from reversible changes in acute pancreatitis.[6][7] Tobacco smoke and alcohol misuse are two of the most frequently implicated causes, and the two risk factors are thought to have a synergistic effect with regards to the development of chronic pancreatitis.[4] Chronic pancreatitis is a risk factor for the development of pancreatic cancer.[4]

  1. ^ a b "Chronic pancreatitis: MedlinePlus Medical Encyclopedia". www.nlm.nih.gov. Archived from the original on 2001-08-06. Retrieved 2015-11-29.
  2. ^ a b c Cite error: The named reference medlineplus was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference uni_chicago_medicine was invoked but never defined (see the help page).
  4. ^ a b c d e Cite error: The named reference Vege 2022 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference emed was invoked but never defined (see the help page).
  6. ^ Brock C, Nielsen LM, Drewes AM, Lelic D (14 November 2013). "Pathophysiology of chronic pancreatitis". World Journal of Gastroenterology. 19 (42): 7231–7240. doi:10.3748/wjg.v19.i42.7231. PMC 3831204. PMID 24259953.
  7. ^ "Chronic Pancreatitis". The Lecturio Medical Concept Library. 11 November 2020. Archived from the original on 9 July 2021. Retrieved 9 July 2021.

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