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Clinical data | |
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AHFS/Drugs.com | Monograph |
MedlinePlus | a682542 |
Routes of administration | Oral |
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Pharmacokinetic data | |
Bioavailability | 39.2% |
Metabolism | Hepatic |
Elimination half-life | 21.3 hours |
Excretion | Renal |
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Chemical and physical data | |
Formula | C21H26ClNO |
Molar mass | 343.90 g·mol−1 |
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Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects.[1] Like all first-generation antihistamines, it is sedating.[2][3]
Patented in 1960, it came into medical use in 1967.[4]
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