Curcumin

Curcumin
	; Enol form
	; Keto form
Names
Pronunciation	/ˈkɜːrkjʊmɪn/
	Preferred IUPAC name (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
	Other names (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; Diferuloylmethane; Curcumin I; C.I. 75300; Natural Yellow 3;
Identifiers
CAS Number	458-37-7 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:3962 ;
ChEMBL	ChEMBL116438 ;
ChemSpider	839564 ;
ECHA InfoCard	100.006.619
E number	E100 (colours)
IUPHAR/BPS	7000;
KEGG	C10443;
PubChem CID	969516;
UNII	IT942ZTH98 ;
CompTox Dashboard (EPA)	DTXSID8031077 ;
	InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ Key: VFLDPWHFBUODDF-FCXRPNKRSA-N ; InChI=1/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ Key: VFLDPWHFBUODDF-FCXRPNKRBF;
	SMILES O=C(\C=C\c1ccc(O)c(OC)c1)CC(=O)\C=C\c2cc(OC)c(O)cc2;
Properties
Chemical formula	C21H20O6
Molar mass	368.385 g·mol−1
Appearance	Bright yellow-orange powder
Melting point	183 °C (361 °F; 456 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Curcumin is a bright yellow chemical produced by plants of the Curcuma longa species. It is the principal curcuminoid of turmeric (Curcuma longa), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cosmetics ingredient, food flavoring, and food coloring.^[1]

Chemically, curcumin is a polyphenol, more particularly a diarylheptanoid, belonging to the group of curcuminoids, which are phenolic pigments responsible for the yellow color of turmeric.^[2]

Laboratory and clinical research have not confirmed any medical use for curcumin. It is difficult to study because it is both unstable and poorly bioavailable. It is unlikely to produce useful leads for drug development as a lead compound.^[3]

^ Majeed S (28 December 2015). "The State of the Curcumin Market". Natural Products Insider. Archived from the original on October 17, 2017. Retrieved February 29, 2016.
^ CID 969516 from PubChem
^ Cite error: The named reference nelson was invoked but never defined (see the help page).

[:0-1] Majeed S (28 December 2015). "The State of the Curcumin Market". Natural Products Insider. Archived from the original on October 17, 2017. Retrieved February 29, 2016.

[pubchem-2] CID 969516 from PubChem

[nelson-3] Cite error: The named reference nelson was invoked but never defined (see the help page).

[1]

[2]

[3]

Names
Enol form
Keto form


Pronunciation	/ˈkɜːrkjʊmɪn/
Preferred IUPAC name (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Other names (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione Diferuloylmethane Curcumin I C.I. 75300 Natural Yellow 3
Identifiers
CAS Number	458-37-7^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:3962^Y
ChEMBL	ChEMBL116438^N
ChemSpider	839564^Y
ECHA InfoCard	100.006.619
E number	E100 (colours)
IUPHAR/BPS	7000
KEGG	C10443
PubChem CID	969516
UNII	IT942ZTH98^Y
CompTox Dashboard (EPA)	DTXSID8031077
InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+^Y Key: VFLDPWHFBUODDF-FCXRPNKRSA-N^Y InChI=1/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ Key: VFLDPWHFBUODDF-FCXRPNKRBF
SMILES O=C(\C=C\c1ccc(O)c(OC)c1)CC(=O)\C=C\c2cc(OC)c(O)cc2
Properties
Chemical formula	C₂₁H₂₀O₆
Molar mass	368.385 g·mol⁻¹
Appearance	Bright yellow-orange powder
Melting point	183 °C (361 °F; 456 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references