Cyclin B

cyclin B2
cyclin B2
Identifiers
Symbol	CCNB2
NCBI gene	9133
HGNC	1580
OMIM	602755
RefSeq	NM_004701
UniProt	O95067
Other data
Locus	Chr. 15 q21.3
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Search for
Structures	Swiss-model
Domains	InterPro

cyclin B1
cyclin B1
	Structure of human cyclin B.
Identifiers
Symbol	CCNB1
Alt. symbols	CCNB
NCBI gene	891
HGNC	1579
OMIM	123836
RefSeq	NM_031966
UniProt	P14635
Other data
Locus	Chr. 5 q12
Structures
Search for
Structures	Swiss-model
Domains	InterPro

cyclin B3

Identifiers

Symbol

CCNB3

Other data

Chr. X p11

Search for
Structures	Swiss-model
Domains	InterPro

Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle^[2] until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present).^[3] The complex of Cdk and cyclin B is called maturation promoting factor or mitosis promoting factor (MPF).

^ PDB: 2B9R; Petri, E.T.; Errico, A.; Escobedo, L.; Hunt, T. & Basavappa, R. (2007). "The crystal structure of human cyclin B". Cell Cycle. 6 (11): 1342–9. doi:10.4161/cc.6.11.4297. PMID 17495533.
^ Ito M (August 2000). "Factors controlling cyclin B expression" (PDF). Plant Mol. Biol. 43 (5–6): 677–90. doi:10.1023/A:1006336005587. PMID 11089869. S2CID 19593310.^{[permanent dead link]}
^ Hershko A (September 1999). "Mechanisms and regulation of the degradation of cyclin B". Philos. Trans. R. Soc. Lond. B Biol. Sci. 354 (1389): 1571–5, discussion 1575–6. doi:10.1098/rstb.1999.0500. PMC 1692665. PMID 10582242.

[pmid17495533-1] PDB: 2B9R; Petri, E.T.; Errico, A.; Escobedo, L.; Hunt, T. & Basavappa, R. (2007). "The crystal structure of human cyclin B". Cell Cycle. 6 (11): 1342–9. doi:10.4161/cc.6.11.4297. PMID 17495533.

[pmid11089869-2] Ito M (August 2000). "Factors controlling cyclin B expression" (PDF). Plant Mol. Biol. 43 (5–6): 677–90. doi:10.1023/A:1006336005587. PMID 11089869. S2CID 19593310.^{[permanent dead link]}

[pmid10582242-3] Hershko A (September 1999). "Mechanisms and regulation of the degradation of cyclin B". Philos. Trans. R. Soc. Lond. B Biol. Sci. 354 (1389): 1571–5, discussion 1575–6. doi:10.1098/rstb.1999.0500. PMC 1692665. PMID 10582242.

[1]

[2]

[3]