Dopamine agonist

Dopamine agonist
Drug class
The skeletal structure of dopamine
Class identifiers
Use	Parkinson's disease, hyperprolactinemia, restless legs syndrome
ATC code	N04BC
Biological target	Dopamine receptors
External links
MeSH	D010300
Legal status
In Wikidata

A dopamine agonist (DA) is a compound that activates dopamine receptors. There are two families of dopamine receptors, D₁-like and D₂-like. They are all G protein-coupled receptors. D₁- and D₅-receptors belong to the D₁-like family and the D₂-like family includes D₂, D₃ and D₄ receptors.^[1] Dopamine agonists are primarily used in the treatment of Parkinson's disease, and to a lesser extent, in hyperprolactinemia and restless legs syndrome.^[2] They are also used off-label in the treatment of clinical depression. The use of dopamine agonists is associated with impulse control disorders and dopamine agonist withdrawal syndrome (DAWS).^[3]