Dopamine antagonist

Dopamine receptor antagonist
Dopaminergic blockers
Drug class
Haloperidol
Class identifiers
UseSchizophrenia, bipolar disorder, nausea and vomiting, etc.
ATC codeN05A
Biological targetDopamine receptors
External links
MeSHD012559
Legal status
In Wikidata

A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors by receptor antagonism. Most antipsychotics are dopamine antagonists, and as such they have found use in treating schizophrenia, bipolar disorder, and stimulant psychosis.[1] Several other dopamine antagonists are antiemetics used in the treatment of nausea and vomiting.

  1. ^ Beaulieu JM, Gainetdinov RR (March 2011). "The physiology, signaling, and pharmacology of dopamine receptors". Pharmacological Reviews. 63 (1): 182–217. doi:10.1124/pr.110.002642. PMID 21303898. S2CID 2545878.

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