Dyslipidemia

Dyslipidemia
An example of dyslipidemia in the form of a 4-ml sample of hyperlipidemic blood in a vacutainer with EDTA. Left to settle for four hours without centrifugation, the lipids separated into the top fraction.
SpecialtyCardiology
SymptomsAtherosclerosis
ComplicationsCardiovascular disease, coronary artery disease
TypesHyperlipidemia, hypolipidemia

Dyslipidemia is a metabolic disorder characterized by abnormally high or low amounts of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood.[1] Dyslipidemia is a risk factor for the development of atherosclerotic cardiovascular diseases (ASCVD),[1] which include coronary artery disease, cerebrovascular disease, and peripheral artery disease.[1] Although dyslipidemia is a risk factor for ASCVD, abnormal levels don't mean that lipid lowering agents need to be started.[2] Other factors, such as comorbid conditions and lifestyle in addition to dyslipidemia, is considered in a cardiovascular risk assessment.[3] In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood. This is often due to diet and lifestyle. Prolonged elevation of insulin resistance can also lead to dyslipidemia.[1] Likewise, increased levels of O-GlcNAc transferase (OGT) may cause dyslipidemia.[citation needed]

  1. ^ a b c d Dixon, Dave L; Riche, Daniel M (April 21, 2021). "Dyslipidemia". Pharmacotherapy:A Pathophysiological Approach, 11e. Book authored by Joseph T. DiPiro, Gary C. Yee, L. Michael Posey, Stuart T. Haines, Thomas D. Nolin, Vicki Ellingrod. Archived from the original on 2020-08-08.
  2. ^ Rosenson, Robert S; Eckel, Robert H (April 9, 2021). "Hypertriglyceridemia". UpToDate. Retrieved April 21, 2021.
  3. ^ Wilson, Peter WF (March 29, 2020). "Cardiovascular disease risk assessment for primary prevention in adults: Our approach". UpToDate. Retrieved April 22, 2021.

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