Elizabeth Gould (psychologist)

Elizabeth Gould
Born1962 (age 61–62)
Alma materUCLA
Scientific career
FieldsNeuroscience
InstitutionsPrinceton University

Elizabeth Gould (born 1962)[1] is an American neuroscientist and the Dorman T. Warren Professor of Psychology at Princeton University.[2][3] She was an early investigator of adult neurogenesis in the hippocampus, a research area that continues to be controversial.[4][5][6] In November 2002, Discover magazine listed her as one of the 50 most important women scientists.[7]

Gould discovered evidence of adult neurogenesis in the hippocampus and olfactory bulb of rats, marmosets and macaque monkeys. In her early studies, she laid the groundwork for understanding the relationship between stress and adult neurogenesis. Specifically, she and Dr. Heather A. Cameron reported on adrenal steroid control of adult neurogenesis in rat dentate gyrus.[8] Additionally, her work has provided evidence of neurogenesis in the adult primate neocortex.[9] Gould and the researchers reported new neurons in adult marmoset monkeys are added to three neocortical association areas important in cognitive function: the prefrontal, inferior temporal and posterior parietal cortex. The new neurons appeared to originate in the subventricular zone, where stem cells giving rise to other cell types are located. They then migrate through the white matter to the neocortex, extending axons. Continual addition of neurons in adulthood apparently contributes to association neocortex functions.[4]

  1. ^ Cite error: The named reference Specter was invoked but never defined (see the help page).
  2. ^ "Elizabeth Gould, Ph.D." Brain and Behavior. 2017-04-03. Retrieved 28 September 2018.
  3. ^ "Elizabeth Gould". Princeton Neuroscience Institute. Retrieved 28 September 2018.
  4. ^ a b Cite error: The named reference Epp was invoked but never defined (see the help page).
  5. ^ Kempermann, Gerd; Gage, Fred H.; Aigner, Ludwig; et al. (19 April 2018). "Human Adult Neurogenesis: Evidence and Remaining Questions". Cell Stem Cell. 23 (1): 25–30. doi:10.1016/J.STEM.2018.04.004. ISSN 1934-5909. PMC 6035081. PMID 29681514. Wikidata Q52804530.
  6. ^ Andreae, Laura C. (11 April 2018). "Adult neurogenesis in humans: Dogma overturned, again and again?". Science Translational Medicine. 10 (436): eaat3893. doi:10.1126/SCITRANSLMED.AAT3893. ISSN 1946-6234. Wikidata Q64385753.
  7. ^ Svitil, Kathy (1 November 2002). "The 50 Most Important Women in Science". Discover. Retrieved 21 December 2014.
  8. ^ Cameron, H.A.; Gould, E. (July 1994). "Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus". Neuroscience. 61 (2): 203–209. doi:10.1016/0306-4522(94)90224-0. PMID 7969902. S2CID 16297590.
  9. ^ Gould, Elizabeth; Reeves, Alison J.; Graziano, Michael S. A.; Gross, Charles G. (October 1999). "Neurogenesis in the Neocortex of Adult Primates". Science. 286 (5439): 548–552. doi:10.1126/science.286.5439.548. PMID 10521353. S2CID 14687148.

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