Enzyme Function Initiative

Enzyme Function Initiative (EFI)
Formation2010
PurposeDevelop and disseminate a robust strategy to determine enzyme function
HeadquartersUniversity of Illinois, Urbana-Champaign
Principal Investigator
John A. Gerlt, Ph.D.
Budget
Five-year NIGMS Glue Grant
Websitewww.enzymefunction.org

The Enzyme Function Initiative (EFI) is a large-scale collaborative project aiming to develop and disseminate a robust strategy to determine enzyme function through an integrated sequence–structure-based approach.[1] The project was funded in May 2010 by the National Institute of General Medical Sciences as a Glue Grant which supports the research of complex biological problems that cannot be solved by a single research group.[2][3] The EFI was largely spurred by the need to develop methods to identify the functions of the enormous number proteins discovered through genomic sequencing projects.[4]

  1. ^ "New NIGMS 'Glue Grant' Takes Aim at Unknown Enzymes" (Press release). NIGMS. 2010-05-20. Archived from the original on 2012-04-27. Retrieved 2012-04-27.
  2. ^ "Glue Grants". NIGMS. Archived from the original on 2013-06-03. Retrieved 2012-04-27.
  3. ^ "PAR-07-412: Large-Scale Collaborative Project Awards (R24/U54)". NIH/NIGMS. Retrieved 2012-04-27.
  4. ^ "Researchers Awarded $33.9 Million Grant to Study Enzyme Functions" (Press release). UIUC News Bureau. 2010-05-20. Retrieved 2012-04-27.

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