Estradiol enantate/algestone acetophenide

Estradiol enantate /
algestone acetophenide
Combination of
Estradiol enantateEstrogen
Algestone acetophenideProgestogen
Clinical data
Trade namesPerlutal, Topasel, Unalmes, Yectames, many others
Other namesEstradiol enantate/dihydroxy­progesterone acetophenide; E2-EN/DHPA
Routes of
administration
Intramuscular injection
Identifiers
CAS Number
PubChem CID
UNII

Estradiol enantate/algestone acetophenide, also known as estradiol enantate/dihydroxyprogesterone acetophenide (E2-EN/DHPA) and sold under the brand names Perlutal and Topasel among others, is a form of combined injectable birth control which is used to prevent pregnancy.[1][2][3] It contains estradiol enantate (E2-EN), an estrogen, and algestone acetophenide (dihydroxyprogesterone acetophenide; DHPA), a progestin.[1][2][3] The medication is given once a month by injection into muscle.[1][2][3]

E2-EN/DHPA is used widely throughout Latin America, is also marketed in Hong Kong, and was previously available in Portugal and Spain as well but was discontinued in these countries.[1][2][3][4]

  1. ^ a b c d Garza-Flores J (April 1994). "Pharmacokinetics of once-a-month injectable contraceptives". Contraception. 49 (4): 347–59. doi:10.1016/0010-7824(94)90032-9. PMID 8013219.
  2. ^ a b c d Sang GW (April 1994). "Pharmacodynamic effects of once-a-month combined injectable contraceptives". Contraception. 49 (4): 361–85. doi:10.1016/0010-7824(94)90033-7. PMID 8013220.
  3. ^ a b c d Bagade O, Pawar V, Patel R, Patel B, Awasarkar V, Diwate S (2014). "Increasing use of long-acting reversible contraception: safe, reliable, and cost-effective birth control" (PDF). World J Pharm Pharm Sci. 3 (10): 364–392. ISSN 2278-4357.
  4. ^ Cite error: The named reference Micromedex was invoked but never defined (see the help page).

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