Exchange transfusion

Exchange transfusion
Exchange transfusion
Other names	Exsanguination transfusion, replacement transfusion, substitution transfusion
ICD-9	99.01
MeSH	D005078
OPS-301 code	8-801
MedlinePlus	002923
	[edit on Wikidata]

An exchange transfusion is a blood transfusion in which the patient's blood or components of it are exchanged with (replaced by) other blood or blood products.^[1] The patient's blood is removed and replaced by donated blood or blood components. This exchange transfusion can be performed manually or using a machine (apheresis).^[2]

Most blood transfusions involve adding blood or blood products without removing any blood, these are also known as simple transfusions or top-up transfusions.^[3]^[4]

Exchange transfusion is used in the treatment of a number of diseases, including sickle-cell disease and hemolytic disease of the newborn. Partial exchange might be required for polycythemia.

Nearly all exchange transfusions are allogeneic (that is, the new blood or blood products come from another person or persons, via donated blood); autologous exchange transfusion is possible (using autologous blood banking), but there are not many situations in which a need for it arises, as most autologous transfusions involve no exchange.

^ "Exchange transfusion". Nlm.nih.gov. MedlinePlus.
^ "Spectra Optia for automatic red blood cell exchange in patients with sickle cell disease | Guidance and guidelines | NICE". www.nice.org.uk. 2 March 2016. Retrieved 2019-01-04.
^ Davis, Bernard A.; Allard, Shubha; Qureshi, Amrana; Porter, John B.; Pancham, Shivan; Win, Nay; Cho, Gavin; Ryan, Kate (2017). "Guidelines on red cell transfusion in sickle cell disease. Part I: principles and laboratory aspects". British Journal of Haematology. 176 (2): 179–191. doi:10.1111/bjh.14346. ISSN 1365-2141. PMID 28092109. S2CID 3462324.
^ "Evidence-Based Management of Sickle Cell Disease: Expert Panel Report, 2014 | National Heart, Lung, and Blood Institute (NHLBI)". www.nhlbi.nih.gov. Retrieved 2019-01-04.

[:0-1] "Exchange transfusion". Nlm.nih.gov. MedlinePlus.

[2] "Spectra Optia for automatic red blood cell exchange in patients with sickle cell disease | Guidance and guidelines | NICE". www.nice.org.uk. 2 March 2016. Retrieved 2019-01-04.

[:1-3] Davis, Bernard A.; Allard, Shubha; Qureshi, Amrana; Porter, John B.; Pancham, Shivan; Win, Nay; Cho, Gavin; Ryan, Kate (2017). "Guidelines on red cell transfusion in sickle cell disease. Part I: principles and laboratory aspects". British Journal of Haematology. 176 (2): 179–191. doi:10.1111/bjh.14346. ISSN 1365-2141. PMID 28092109. S2CID 3462324.

[:2-4] "Evidence-Based Management of Sickle Cell Disease: Expert Panel Report, 2014 | National Heart, Lung, and Blood Institute (NHLBI)". www.nhlbi.nih.gov. Retrieved 2019-01-04.

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