Fruit flies in space

On a July 9, 1946, suborbital V-2 rocket flight, fruit flies became the first living and sentient organisms to go to space, and on February 20, 1947, fruit flies safely returned from a suborbital space flight, which paved the way for human exploration. For years before sending mammals into space, such as the 1949 flight of the rhesus monkey Albert II, the Soviet space dogs, or humans, scientists studied Drosophila melanogaster (the common fruit fly) and its reactions to both radiation and space flight to understand the possible effects of space and a zero-gravity environment on humans. Starting in the 1910s, researchers conducted experiments on fruit flies because humans and fruit flies share many genes.

At the height of the Cold War and the Space Race, flies were sent on missions to space with great frequency, allowing scientists to study the nature of living and breeding in space. Scientists and researchers from the Soviet Union and the United States both used fruit flies for their research and missions. These flies were used to further the understanding of the effects of weightlessness on the cardiovascular system, the immune system, and the genes of astronauts.