Back هانس كريبس Arabic هانس كريبس (دكتور من المملكه المتحده) ARZ هانس آدولف کربس AZB Ханс Адольф Крэбс Byelorussian Ханс Адолф Кребс Bulgarian হ্যান্স অ্যাডলফ ক্রেবস Bengali/Bangla Hans Adolf Krebs Catalan ھانس ئەدۆڵف کریبس CKB Hans Adolf Krebs Czech Hans Krebs Welsh
Hans Krebs | |
|---|---|
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| Born | 25 August 1900 |
| Died | 22 November 1981 (aged 81) Oxford, England |
| Nationality | German |
| Citizenship | Naturalised British (from 1939) |
| Alma mater | University of Göttingen University of Freiburg University of Berlin University of Hamburg |
| Known for | Citric acid cycle Urea cycle Glyoxylate cycle Krebs–Henseleit solution |
| Spouse |
Margaret Cicely Fieldhouse
(m. 1938) |
| Children | Paul, John, and Helen |
| Awards | Albert Lasker Award for Basic Medical Research (1953) Nobel Prize in Physiology or Medicine (1953) Royal Medal (1954) Copley Medal (1961) |
| Scientific career | |
| Fields | Internal medicine, biochemistry |
| Institutions | Kaiser Wilhelm Institute for Biology University of Hamburg University of Cambridge University of Sheffield University of Oxford |
Sir Hans Adolf Krebs, FRS (/krɛbz, krɛps/, German: [hans ˈʔaːdɔlf ˈkʁeːps] ; 25 August 1900 – 22 November 1981)[1][2][3][4] was a German-British biologist, physician and biochemist.[5] He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life.[6][7] He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of nearly all organisms, including humans, other than anaerobic microorganisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the sequence of metabolic reactions that allows cells of oxygen-respiring organisms to obtain far more ATP from the food they consume than anaerobic processes such as glycolysis can supply; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle,[8] a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi.
Krebs died in 1981 in Oxford, where he had spent 13 years of his career from 1954 until his retirement in 1967 at the University of Oxford.
- ^ Kornberg, H.; Williamson, D. H. (1984). "Hans Adolf Krebs. 25 August 1900 – 22 November 1981". Biographical Memoirs of Fellows of the Royal Society. 30: 350–385. doi:10.1098/rsbm.1984.0013. PMID 11616005.
- ^ Weber, George (2001). "Sir Hans A. Krebs Centenary Lecture: cancer and clinical targeting". Advances in Enzyme Regulation. 41 (1): 1–29. doi:10.1016/S0065-2571(00)00026-1. PMID 11417529.
- ^ Gibbons, Marion Stubbs, Geoff (2000). "Hans Adolf Krebs (1900–1981)...His Life and Times". IUBMB Life. 50 (3): 163–166. doi:10.1080/152165400300001462. PMID 11142342. S2CID 26393428.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Raju, Tonse NK (1999). "The Nobel Chronicles". The Lancet. 353 (9164): 1628. doi:10.1016/S0140-6736(05)75758-5. PMID 10334294. S2CID 54354255.
- ^ "Sir Hans Adolf Krebs". Encyclopædia Britannica, Inc. Retrieved 26 July 2014.
- ^ Leigh, F W (2009). "Sir Hans Adolf Krebs (1900–81), pioneer of modern medicine, architect of intermediary metabolism". Journal of Medical Biography. 17 (3): 149–154. doi:10.1258/jmb.2009.009032. PMID 19723965. S2CID 207200346.
- ^ Edsall, John T (1993). "Master of metabolic cycles". Nature. 366 (6454): 417–418. Bibcode:1993Natur.366..417E. doi:10.1038/366417a0. S2CID 4241345.
- ^ Cite error: The named reference
glyoxwas invoked but never defined (see the help page).
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