Chorionic gonadotropin, alpha polypeptide | |||||||
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Identifiers | |||||||
Symbol | CGA | ||||||
Alt. symbols | FSHA, GPHa, GPHA1, HCG, LHA, TSHA | ||||||
NCBI gene | 1081 | ||||||
HGNC | 1885 | ||||||
OMIM | 118850 | ||||||
RefSeq | NM_000735 | ||||||
UniProt | P01215 | ||||||
Other data | |||||||
Locus | Chr. 6 q14-q21 | ||||||
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chorionic gonadotropin, beta polypeptide | |||||||
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Identifiers | |||||||
Symbol | CGB | ||||||
Alt. symbols | CGB3 | ||||||
NCBI gene | 1082 | ||||||
HGNC | 1886 | ||||||
OMIM | 118860 | ||||||
RefSeq | NM_000737 | ||||||
UniProt | P01233 | ||||||
Other data | |||||||
Locus | Chr. 19 q13.3 | ||||||
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Human chorionic gonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells that are surrounding a growing embryo (syncytiotrophoblast initially), which eventually forms the placenta after implantation.[1][2] The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests). Some cancerous tumors produce this hormone; therefore, elevated levels measured when the patient is not pregnant may lead to a cancer diagnosis and, if high enough, paraneoplastic syndromes, however, it is unknown whether this production is a contributing cause or an effect of carcinogenesis. The pituitary analog of hCG, known as luteinizing hormone (LH), is produced in the pituitary gland of males and females of all ages.[1][3]
Beta-hCG is initially secreted by the syncytiotrophoblast.[citation needed]
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