IL36G

IL36G
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4IZE, 4P0J, 4P0K, 4P0L
Identifiers
Aliases	IL36G, interleukin 36, gamma, IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1H1, IL1RP2, IL1F9, interleukin 36 gamma
External IDs	OMIM: 605542; MGI: 2449929; HomoloGene: 49595; GeneCards: IL36G; OMA:IL36G - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	112,985,658 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,083,580 bp
RNA expression pattern
	Top expressed in
	periodontal fiber; ; testicle; ; gums; ; gingival epithelium; ; skin of leg; ; cartilage tissue; ; gonad; ; skin of abdomen; ; human penis; ; body of tongue;
	Top expressed in
	granulocyte; ; esophagus; ; gastrula; ; belly cord; ; lip; ; skin of external ear; ; tibiofemoral joint; ; blood; ; cervix; ; skin of back;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; interleukin-1 receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	cell-cell signaling; innate immune response; inflammatory response; immune system process; immune response; regulation of signaling receptor activity; cytokine-mediated signaling pathway; neutrophil chemotaxis; positive regulation of interleukin-6 production; positive regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of myoblast differentiation; positive regulation of JNK cascade; cellular response to lipopolysaccharide; negative regulation of myoblast fusion;
	Sources:Amigo / QuickGO
Orthologs
	56300
	215257
	ENSG00000136688
	ENSMUSG00000044103
	Q9NZH8
	Q8R460; Q3U0P4
	NM_001278568; NM_019618
	NM_153511
	NP_001265497; NP_062564
	NP_705731
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-36 gamma previously known as interleukin-1 family member 9 (IL1F9) is a protein that in humans is encoded by the IL36G gene.^[5]^[6]^[7]^[8]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136688 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044103 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Busfield SJ, Comrack CA, Yu G, Chickering TW, Smutko JS, Zhou H, Leiby KR, Holmgren LM, Gearing DP, Pan Y (June 2000). "Identification and gene organization of three novel members of the IL-1 family on human chromosome 2". Genomics. 66 (2): 213–6. doi:10.1006/geno.2000.6184. PMID 10860666.
^ Kumar S, McDonnell PC, Lehr R, Tierney L, Tzimas MN, Griswold DE, Capper EA, Tal-Singer R, Wells GI, Doyle ML, Young PR (April 2000). "Identification and initial characterization of four novel members of the interleukin-1 family". The Journal of Biological Chemistry. 275 (14): 10308–14. doi:10.1074/jbc.275.14.10308. PMID 10744718.
^ Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002). "A sequence-based map of the nine genes of the human interleukin-1 cluster". Genomics. 79 (5): 718–25. doi:10.1006/geno.2002.6751. PMID 11991722.
^ Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002). "Genomic organization of the interleukin-1 locus". Genomics. 79 (5): 726–33. doi:10.1006/geno.2002.6752. PMID 11991723.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136688 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044103 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10860666-5] Busfield SJ, Comrack CA, Yu G, Chickering TW, Smutko JS, Zhou H, Leiby KR, Holmgren LM, Gearing DP, Pan Y (June 2000). "Identification and gene organization of three novel members of the IL-1 family on human chromosome 2". Genomics. 66 (2): 213–6. doi:10.1006/geno.2000.6184. PMID 10860666.

[pmid10744718-6] Kumar S, McDonnell PC, Lehr R, Tierney L, Tzimas MN, Griswold DE, Capper EA, Tal-Singer R, Wells GI, Doyle ML, Young PR (April 2000). "Identification and initial characterization of four novel members of the interleukin-1 family". The Journal of Biological Chemistry. 275 (14): 10308–14. doi:10.1074/jbc.275.14.10308. PMID 10744718.

[pmid11991722-7] Nicklin MJ, Barton JL, Nguyen M, FitzGerald MG, Duff GW, Kornman K (May 2002). "A sequence-based map of the nine genes of the human interleukin-1 cluster". Genomics. 79 (5): 718–25. doi:10.1006/geno.2002.6751. PMID 11991722.

[pmid11991723-8] Taylor SL, Renshaw BR, Garka KE, Smith DE, Sims JE (May 2002). "Genomic organization of the interleukin-1 locus". Genomics. 79 (5): 726–33. doi:10.1006/geno.2002.6752. PMID 11991723.

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