Jamaican vomiting sickness

Jamaican vomiting sickness
Jamaican vomiting sickness
Specialty	Toxicology

Jamaican vomiting sickness, also known as toxic hypoglycemic syndrome (THS),^[1] acute ackee fruit intoxication,^[2] or ackee poisoning,^[1] is an acute illness caused by the toxins hypoglycin A and hypoglycin B, which are present in fruit of the ackee tree. While in the fully ripened arils, hypoglycin A is at levels of less than 0.1 ppm, in unripe arils it can be over 1000 ppm^[3] and can cause vomiting and even death. Some countries in the Caribbean and Western Africa experience frequent cases.^[4]

^ ^a ^b Gordon, André (2015-01-01), Gordon, André (ed.), "Chapter 4 - Biochemistry of Hypoglycin and Toxic Hypoglycemic Syndrome", Food Safety and Quality Systems in Developing Countries, San Diego: Academic Press, pp. 47–61, doi:10.1016/b978-0-12-801227-7.00004-4, ISBN 978-0-12-801227-7, retrieved 2020-07-05
^ "The portal for rare diseases and orphan drugs". Retrieved 5 July 2020.
^ Medscape- Toxicity, Plants - Ackee Fruit
^ "Jamaican vomiting sickness | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Archived from the original on 2021-06-08. Retrieved 2018-04-17.

[:0-1] Gordon, André (2015-01-01), Gordon, André (ed.), "Chapter 4 - Biochemistry of Hypoglycin and Toxic Hypoglycemic Syndrome", Food Safety and Quality Systems in Developing Countries, San Diego: Academic Press, pp. 47–61, doi:10.1016/b978-0-12-801227-7.00004-4, ISBN 978-0-12-801227-7, retrieved 2020-07-05

[2] "The portal for rare diseases and orphan drugs". Retrieved 5 July 2020.

[medscape-3] Medscape- Toxicity, Plants - Ackee Fruit

[4] "Jamaican vomiting sickness | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Archived from the original on 2021-06-08. Retrieved 2018-04-17.

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